Emapunil
Cat. No.：YN481437
CAS No. ：226954-04-7
规格
价格(RMB)
库存
| 产品名称: | Emapunil |
| CAS No.: | 226954-04-7 |
| Chemical Name: | N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide |
| Synonyms: | AC-5216; XBD-173 |
| 分子量: | 401.46 |
| 分子式: | C₂₃H₂₃N₅O₂ |
| SMILES: | O=C(N(CC)CC1=CC=CC=C1)CN2C(N(C)C3=CN=C(C4=CC=CC=C4)N=C23)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Emapunil (AC-5216) 是口服有效的、选择性的TSPO(一种线粒体苯二氮受体) 的配体，在多种动物模型中表现出抗焦虑和抗抑郁活性。 |
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Kita, A., Kohayakawa, H., Kinoshita, T., et al.Antianxiety and antidepressant-like effects of AC-5216, a novel mitochondrial benzodiazepine receptor ligandBr. J. Pharmacol.142,1059-1072(2004)
Qiu, Z.K., Zhang, L.M., Zhao, N., et al.Repeated administration of AC-5216, a ligand for the 18 kDa translocator protein, improves behavioral deficits in a mouse model of post-traumatic stress disorderProg. Neuropsychopharmacol. Biol. Psychiatry45,40-46(2013)
