Chlorthalidone
Cat. No.：YN481471
CAS No. ：77-36-1
规格
价格(RMB)
库存
| 产品名称: | Chlorthalidone |
| CAS No.: | 77-36-1 |
| Chemical Name: | 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)-benzenesulfonamide |
| Synonyms: | 氯噻酮 |
| 分子量: | 338.77 |
| 分子式: | C₁₄H₁₁ClN₂O₄S |
| SMILES: | O=S(C1=CC(C2(O)NC(C3=C2C=CC=C3)=O)=CC=C1Cl)(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chlorthalidone 是一种噻嗪类利尿剂，有潜力用于高血压的研究。 |
| IC50和靶点: | |
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Roush, G.C., Buddharaju, V., Ernst, M.E., et al.Chlorthalidone: Mechanisms of action and effect on cardiovascular eventsCurr. Hypertens. Rep.15(5),514-521(2013)
Temperini, C., Cecchi, A., Scozzafava, A., et al.Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adductBioorg. Med. Chem. Lett.18(8),2567-2573(2008)
Cabral, A.M., Carvalhinho, F.B., Vasquez, E.C., et al.Effects of chlorthalidone on ventricular hypertrophy in deoxycorticosterone acetate-salt hypertensive ratsHypertension23(1 Suppl),I180-I184(1994)
