Tirasemtiv
Cat. No.:YN481518
产品名称: | Tirasemtiv |
CAS No.: | 1005491-05-3 |
Chemical Name: | 1-(1-ethylpropyl)-6-ethynyl-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one |
Synonyms: | CK-2017357 |
分子量: | 230.27 |
分子式: | C₁₂H₁₄N₄O |
SMILES: | O=C1N(C(CC)CC)C2=NC(C#C)=CN=C2N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tirasemtiv 是一种快速骨骼肌型肌钙蛋白复合物激活剂。 |
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Russell, A.J., Hartman, J.J., Hinken, A.C., et al.Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseasesNat Med.18(3),452-455(2012)
Hwee, D.T., Kennedy, A., Ryans, J., et al.Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse modelPLoS One9(5),e96921(2014)