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Tirasemtiv

Cat. No.:YN481518

  • CAS No. :1005491-05-3

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    • 产品名称: Tirasemtiv
      CAS No.: 1005491-05-3
      Chemical Name: 1-(1-ethylpropyl)-6-ethynyl-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one
      Synonyms:CK-2017357
      分子量:230.27
      分子式:C₁₂H₁₄N₄O
      SMILES:O=C1N(C(CC)CC)C2=NC(C#C)=CN=C2N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tirasemtiv 是一种快速骨骼肌型肌钙蛋白复合物激活剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Russell, A.J., Hartman, J.J., Hinken, A.C., et al.Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseasesNat Med.18(3),452-455(2012)

      Hwee, D.T., Kennedy, A., Ryans, J., et al.Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse modelPLoS One9(5),e96921(2014)

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