P7C3
Cat. No.：YN481519
CAS No. ：301353-96-8
规格
价格(RMB)
库存
| 产品名称: | P7C3 |
| CAS No.: | 301353-96-8 |
| Chemical Name: | 3,6-dibromo-α-[(phenylamino)methyl]-9H-carbazole-9-ethanol |
| Synonyms: | P7C3, 301353-96-8 |
| 分子量: | 474.19 |
| 分子式: | C₂₁H₁₈Br₂N₂O |
| SMILES: | OC(CNC1=CC=CC=C1)CN2C3=CC=C(Br)C=C3C4=CC(Br)=CC=C24 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | P7C3 是一种具有口服活性的，可透过血脑屏障的 aminopropyl carbazole 类化合物，具有神经保护作用。P7C3 可用于神经退行性疾病，包括帕金森病的研究。 |
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Pieper, A.A., Xie, S., Capota, E., et al.Discovery of a pro-neurogenic, neuroprotective chemicalCell142(1),39-51(2010)
De Jesús-Cortés, H., Xu, P., Drawbridge, J., et al.Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson diseaseProc. Natl. Acad. Sci. USA109(42),17010-17015(2012)
Tesla, R., Wolf, H.P., Xu, P., et al.Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosisProc. Natl. Acad. Sci. USA109(42),17016-17021(2012)
Wang, G., Han, T., Nijhawan, D., et al.P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvageCell158(6),1324-1334(2014)
