Benfotiamine
Cat. No.：YN481581
CAS No. ：22457-89-2
规格
价格(RMB)
库存
| 产品名称: | Benfotiamine |
| CAS No.: | 22457-89-2 |
| Chemical Name: | benzenecarbothioic acid, S-[2-[[(4-amino-2-methyl-5-pyrimidinyl)methyl]formylamino]-1-[2-(phosphonooxy)ethyl]-1-propen-1-yl] ester |
| Synonyms: | 苯磷硫胺; S-Benzoylthiamine O-monophosphate |
| 分子量: | 466.45 |
| 分子式: | C₁₉H₂₃N₄O₆PS |
| SMILES: | CC1=NC=C(CN(/C(C)=C(CCOP(O)(O)=O)/SC(C2=CC=CC=C2)=O)C=O)C(N)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Benfotiamine (S-Benzoylthiamine O-monophosphate) 是维生素 B1 的脂溶性类似物，具有比维生素B1更高的吸收率和生物利用度，常用作糖尿病并发症的食品补充剂。Benfotiamine 具有直接抗氧化能力，可防止DNA损伤。 |
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Stracke, H., Hammes, H.P., Werkmann, D., et al.Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic ratsExp. Clin. Endocrinol. Diabetes109(6),330-336(2001)
Pomero, F., Molinar Min, A., La Selva, M., et al.Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucoseActa. Diabetol.38(3),135-138(2001)
Babaei-Jadidi, R., Karachalias, N., Ahmed, N., et al.Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamineDiabetes52(8),2110-2120(2003)
Portari, G.V., Ovidio, P.P., Deminice, R., et al.Protective effect of treatment with thiamine or benfotiamine on liver oxidative damage in rat model of acute ethanol intoxicationLife Sci.162,21-24(2016)
Pan, X., Gong, N., Zhao, J., et al.Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic miceBrain133(Pt 5),1342-1351(2010)
