Atomoxetine hydrochloride
Cat. No.：YN481583
CAS No. ：82248-59-7
规格
价格(RMB)
库存
| 产品名称: | Atomoxetine hydrochloride |
| CAS No.: | 82248-59-7 |
| Chemical Name: | N-methyl-γR-(2-methylphenoxy)-benzenepropanamine, monohydrochloride |
| Synonyms: | 盐酸托莫西汀; Tomoxetine hydrochloride; LY 139603; (R)-Tomoxetine hydrochloride |
| 分子量: | 291.82 |
| 分子式: | C₁₇H₂₂ClNO |
| SMILES: | CC1=CC=CC=C1O[C@@H](C2=CC=CC=C2)CCNC.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Atomoxetine hydrochloride 是去甲肾上腺素重吸收抑制剂，与人NET，SERT和DAT的放射性配体结合的Ki分别为5，77和1451 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bymaster, F.P., Katner, J.S., Nelson, D.L., et al.Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: A potential mechanism for efficacy in attention deficit/hyperactivity disorderNeuropsychopharmacology27(5),699-711(2002)
Blondeau, C., and Dellu-Hagedorn, F.Dimensional analysis of ADHD subtypes in ratsBiol. Psychiatry61(12),1340-1350(2007)
Park, J.H., Shin, B.N., Chen, B.H., et al.Neuroprotection and reduced gliosis by atomoxetine pretreatment in a gerbil model of transient cerebral ischemiaJ. Neurol. Sci.359(1-2),373-380(2015)
