Potassium oxonate
Cat. No.：YN481593
CAS No. ：2207-75-2
规格
价格(RMB)
库存
| 产品名称: | Potassium oxonate |
| CAS No.: | 2207-75-2 |
| Chemical Name: | 1,4,5,6-tetrahydro-4,6-dioxo-1,3,5-triazine-2-carboxylic acid, monopotassium salt |
| Synonyms: | 氧嗪酸钾; Potassium azaorotate; Potassium otastat |
| 分子量: | 195.17 |
| 分子式: | C₄H₂KN₃O₄ |
| SMILES: | O=C(O[K])C1=NC(O)=NC(O)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Potassium oxonate 是尿酸酶抑制剂，能抑制5-FU磷酸化为5-fluorouridine-5'-monophosphate。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Gralla, E.J., and Crelin, E.S.Oxonic acid and fetal development: I. Embryotoxicity in miceToxicology6(3),289-297(1976)
Yoshisue, K., Masuda, H., Matsushima, E., et al.Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to ratsDrug. Metab. Dispos.28(10),1162-1167(2000)
Chhetri, P., Giri, A., Shakya, S., et al.Current development of anti-cancer drug S-1J. Clin. Diagn. Res.10(11),XE01-XE05(2016)
