Amcasertib
Cat. No.:YN481608
产品名称: | Amcasertib |
CAS No.: | 1129403-56-0 |
Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[[1,2-dihydro-2-oxo-5-(2-phenyl-4-thiazolyl)-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; BBI 503; |
Synonyms: | BBI503 |
分子量: | 539.69 |
分子式: | C₃₁H₃₃N₅O₂S |
SMILES: | O=C(C1=C(C)NC(/C=C2C(NC3=C/2C=C(C4=CSC(C5=CC=CC=C5)=N4)C=C3)=O)=C1C)NCCN(CC)CC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Amcasertib是可以口服注射的产品,能够抑制癌症干细胞途径,通过抑制靶点干细胞靶向激酶,包括Nanog。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Li, C. J., et al.: From PCT Int. Appl. (2009), WO 2009033033 A2 20090312
Chen, H., et al.: Gynecologic Oncology, 157, 783 (2020)