BRD7116
Cat. No.:YN481641
产品名称: | BRD7116 |
CAS No.: | 329059-55-4 |
Chemical Name: | N,N'-(sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide |
Synonyms: | BRD7716 |
分子量: | 496.66 |
分子式: | C₂₈H₃₆N₂O₄S |
SMILES: | O=S(C1=CC=C(NC(C2C(C)(C)C2(C)C)=O)C=C1)(C3=CC=C(NC(C4C(C)(C)C4(C)C)=O)C=C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | BRD7116竞争性地结合到细菌DNA促旋酶, 作用于LSCe 细胞,EC50值为200 nM, 具有非自治性的抗白血病活性。 |
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Hartwell, K.A., Miller, P.G., Mukherjee, S., et al.Niche-based screening identifies small-molecule inhibitors of leukemia stem cellsNat. Chem. Biol.9(12),840-848(2013)