Latanoprostene bunod
Cat. No.:YN481674
产品名称: | Latanoprostene bunod |
CAS No.: | 860005-21-6 |
Chemical Name: | (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptenoic acid, 4-(nitrooxy)butyl ester |
Synonyms: | NCX116; LBN |
分子量: | 507.62 |
分子式: | C₂₇H₄₁NO₈ |
SMILES: | O=C(OCCCCO[N+]([O-])=O)CCC/C=C\C[C@@H]1[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Latanoprostene bunod (NCX116; LBN) 是一种一氧化氮 (NO) 供体前列腺素 F2a 类似物,有潜力用于开角型青光眼或高眼压 (OHT) 患者降低眼压 (IOP) 的局部眼科的研究。 |
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Krauss, A.H.P., Impagnatiello, F., Toris, C.B., et al.Ocular hypotensive activity of BOL-303259-X, a nitric oxide donating prostaglandin F2α agonist, in preclinical modelsExp. Eye Res.93(3),250-255(2011)