FPR Agonist 43
Cat. No.:YN481677
产品名称: | FPR Agonist 43 |
CAS No.: | 903895-98-7 |
Chemical Name: | N-(4-chlorophenyl)-N′-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea |
Synonyms: | |
分子量: | 384.86 |
分子式: | C₂₀H₂₁ClN₄O₂ |
SMILES: | O=C(NC1=C(C(C)C)N(C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(Cl)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | FPR Agonist 43 (compound 43) 是有效的甲酰基肽受体 1 (FPR1) 和甲酰基肽受体 2 (FPR2)/ALX双重激动剂。 |
IC50和靶点: | |
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Bürli, R.W., Xu, H., Zou, X., et al.Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agentsBioorg. Med. Chem. Lett.16(14),3713-3718(2006)
Sogawa, Y., Shimizugawa, A., Ohyama, T., et al.The pyrazolone originally reported to be a formyl peptide receptor (FPR) 2/ALX-selective agonist is instead an FPR1 and FPR2/ALX dual agonistJ. Pharmacol. Sci.111(3),317-321(2009)