BRD7552
Cat. No.：YN481679
CAS No. ：1137359-47-7
规格
价格(RMB)
库存
| 产品名称: | BRD7552 |
| CAS No.: | 1137359-47-7 |
| Chemical Name: | 2,3-bis(N-1,3-benzodioxol-5-ylcarbamate), 4-[N-[4-(ethoxycarbonyl)phenyl]carbamate], methyl, α-D-glucopyranoside |
| Synonyms: | BRD 7552;BRD-7552;Ethyl 4-(((((2R,3R,4S,5R,6S)-4,5-bis((benzo[d][1,3]dioxol-5-ylcarbamoyl)oxy)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3-yl)oxy)carbonyl)amino)benzoate;BRD7552;PK04Pur_000261;AOB2459;BRD7552, >=98% (HPLC);S7363;PK04_094072;A14957;10 |
| 分子量: | 711.63 |
| 分子式: | C₃₃H₃₃N₃O₁₅ |
| SMILES: | OC[C@@H](O1)[C@@H](OC(NC2=CC=C(C(OCC)=O)C=C2)=O)[C@H](OC(NC3=CC=C(OCO4)C4=C3)=O)[C@@H](OC(NC5=CC=C(OCO6)C6=C5)=O)[C@H]1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BRD7552 是一种PDX1转录因子诱导剂，它上调了人类原代胰岛和导管细胞中 PDX1 的表达，并诱导 PDX1 启动子的表观遗传变化与转录激活一致。BRD7552 增加胰岛素表达。PDX1 是参与胰腺发育和β细胞功能的关键转录因子。 |
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| Solvent & Solubility: |
Yuan, Y., Hartland, K., Boxkovic, Z., et al.A small-molecule inducer of PDX1 expression identified by high-throughput screeningChem. Biol.20(12),1513-1522(2013)
