Aramchol
Cat. No.：YN481683
CAS No. ：246529-22-6
规格
价格(RMB)
库存
| 产品名称: | Aramchol |
| CAS No.: | 246529-22-6 |
| Chemical Name: | (3β,5β,7α,12α)-7,12-dihydroxy-3-[(1-oxoeicosyl)amino]-cholan-24-oic acid |
| Synonyms: | C20-FABAC |
| 分子量: | 702.10 |
| 分子式: | C₄₄H₇₉NO₅ |
| SMILES: | C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@@H](NC(CCCCCCCCCCCCCCCCCCC)=O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aramchol (C20-FABAC) 是胆酸和花生酸的结合物，抑制硬脂酰辅酶 A 去饱和酶 1 (SCD1) 的活性。Aramchol 在非酒精性脂肪性肝病 (NAFLD) 和非酒精性脂肪性肝炎 (NASH) 中具有潜在的应用潜能。 |
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Gilat, T., Leikin-Frenkel, A., Goldiner, I., et al.Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer and prevents the formation of cholesterol gallstones in inbred miceLipids36(10),1135-1140(2001)
Gilat, T., Leikin-Frenkel, A., Goldiner, I., et al.Prevention of diet-induced fatty liver in experimental animals by the oral administration of a fatty acid bile acid conjugate (FABAC)Hepatology38(2),436-442(2003)
