ASP-9521
Cat. No.:YN481689
产品名称: | ASP-9521 |
CAS No.: | 1126084-37-4 |
Chemical Name: | [4-(2-hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)-methanone |
Synonyms: | ASP9521 |
分子量: | 330.42 |
分子式: | C₁₉H₂₆N₂O₃ |
SMILES: | O=C(N1CCC(CC(C)(O)C)CC1)C(N2)=CC3=C2C=CC(OC)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ASP-9521是有效,选择性,有口服活性的AKR1C3抑制剂;对人类AKR1C3的IC50值为11 nM。 |
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Kikuchi, A., Furutani, T., Azami, H., et al.In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3).Invest New Drugs32(5),860-870(2014)