ML239
Cat. No.:YN481692
产品名称: | ML239 |
CAS No.: | 1378872-36-6 |
Chemical Name: | 2-(2,4,6-trichlorophenoxy)-acetic acid, (2E)-2-(1H-pyrrol-2-ylmethylene)hydrazide |
Synonyms: | CID-49843203 |
分子量: | 346.60 |
分子式: | C₁₃H₁₀Cl₃N₃O₂ |
SMILES: | O=C(N/N=C/C1=CC=CN1)COC2=C(Cl)C=C(Cl)C=C2Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ML239 是一种有效的选择性的乳腺癌肿瘤干细胞抑制剂,C50值为 1.16 μM。 |
IC50和靶点: | |
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Carmody, L.C., Germain, A.R., VerPlank, L., et al.Phenotypic high-throughput screening elucidates target pathway in breast cancer stem cell-like cellsJ. Biomol. Screen.17(9),1204-1210(2012)
Germain, A.R., Carmody, L.C., Morgan, B., et al.Identification of a selective small molecule inhibitor of breast cancer stem cellsBioorg. Med. Chem. Lett.22(10),3571-3574(2012)
Carmody, L., Garmain, A., Morgan, B., et al.Identification of a selective small-molecule inhibitor of breast cancer stem cells - Probe 11,1-13(2011)