Sapropterin dihydrochloride
Cat. No.：YN481756
CAS No. ：69056-38-8
规格
价格(RMB)
库存
| 产品名称: | Sapropterin dihydrochloride |
| CAS No.: | 69056-38-8 |
| Chemical Name: | 2-amino-6R-(1R,2S-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone, dihydrochloride |
| Synonyms: | 6R-BH4 dihydrochloride; 6R-Tetrahydro-L-biopterin dihydrochloride |
| 分子量: | 314.17 |
| 分子式: | C₉H₁₇Cl₂N₅O₃ |
| SMILES: | O=C1N=C(N)NC2=C1N[C@@H]([C@@H](O)[C@@H](O)C)CN2.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sapropterin dihydrochloride (6R-BH4 dihydrochloride) 是一个合成的 BH4 形式，被批准用于 BH4 反应的 PKU 研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kappock, T.J., and Caradonna, J.P.Pterin-dependent amino acid hydroxylasesChem. Rev.96(7),2659-2756(1996)
Mayer, B., and Werner, E.R.In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxideN.-S. Arch. Pharmacol.351(5),453-463(1995)
Kraft, V.A.N., Bezjian, C.T., Pfeiffer, S., et al.GTP cyclohydrolase 1/tetrahydrobiopterin counteract ferroptosis through lipid remodelingACS Cent. Sci.6(1),41-53(2020)
Soula, M., Weber, R.A., Zilka, O., et al.Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducersNat. Chem. Biol.16(12),1351-1360(2020)
