Chlormethiazole hydrochloride
Cat. No.：YN481768
CAS No. ：6001-74-7
规格
价格(RMB)
库存
| 产品名称: | Chlormethiazole hydrochloride |
| CAS No.: | 6001-74-7 |
| Chemical Name: | 5-(2-chloroethyl)-4-methyl-thiazole, monohydrochloride |
| Synonyms: | Clomethiazole hydrochloride |
| 分子量: | 198.11 |
| 分子式: | C₆H₉Cl₂NS |
| SMILES: | CC1=C(CCCl)SC=N1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clomethiazole hydrochloride 是一种镇静剂和抗惊厥药。Clomethiazole hydrochloride 具有神经保护作用，可抑制 MDMA 诱导的血清素能神经末梢退化。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Nelson, R.M., Green, A.R., and Hainsworth, A.H.Electrophysiological actions of γ-aminobutyric acid and clomethiazole on recombinant GABAA receptorsEur. J. Pharmacol.452(3),255-262(2002)
Pilip, S., Urbańska, E.M., Swiader, M., et al.Anticonvulsant action of chlormethiazole is prevented by subconvulsive amounts of strychnine and aminophylline but not by bicuculline and picrotoxinPol. J. Pharmacol.52(4),267-273(2000)
Sydserff, S.G., Cross, A.J., and Green, A.R.The neuroprotective effect of chlormethiazole on ischaemic neuronal damage following permanent middle cerebral artery ischaemia in the ratNeurodegeneration4(3),323-328(1995)
