Pamidronate Disodium
Cat. No.：YN481771
CAS No. ：57248-88-1
规格
价格(RMB)
库存
| 产品名称: | Pamidronate Disodium |
| CAS No.: | 57248-88-1 |
| Chemical Name: | P,P'-(3-amino-1-hydroxypropylidene)bis-phosphonic acid, disodium salt |
| Synonyms: | CGP 23339A |
| 分子量: | 281.05 |
| 分子式: | C₃H₁₁NNa₂O₇P₂ |
| SMILES: | OP(O)(C(O)(P(O)(O)=O)CCN)=O.[2Na] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pamidronate二钠盐可强化骨骼。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Dunford, J.E., Thompson, K., Coxon, F.P., et al.Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonatesJ. Pharmacol. Exp. Ther.296(2),235-242(2001)
Reitsma, P.H., Bijovet, O.L.M., Verlinden-Ooms, H., et al.Kinetic studies of bone and mineral metabolism during treatment with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD) in ratsCalcif. Tissue Int.32(2),145-157(1980)
Okada, M., Noguchi, S., Hasegawa, Y., et al.Effect of pamidronate in a rat hypercalcemia model induced by cholecalciferolArzneimittelforschung42(4),543-546(1992)
Seol, J.-W., Lee, Y.-J., Jackson, C.J., et al.Activated protein C inhibits bisphosphonate-induced endothelial cell death via the endothelial protein C receptor and nuclear factor-κB pathwaysInt. J. Mol. Med.27(6),835-840(2011)
