Methimazole
Cat. No.：YN481783
CAS No. ：60-56-0
规格
价格(RMB)
库存
| 产品名称: | Methimazole |
| CAS No.: | 60-56-0 |
| Chemical Name: | 1,3-dihydro-1-methyl-2H-imidazole-2-thione |
| Synonyms: | 甲巯咪唑 |
| 分子量: | 114.17 |
| 分子式: | C₄H₆N₂S |
| SMILES: | S=C1NC=CN1C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Methimazole 是一种抗甲状腺化合物，广泛应用于甲亢的研究。Methimazole 具有显著的肝毒性。 |
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Davidson, B., Soodak, M., Neary, J.T., et al.The irreversible inactivation of thyroid peroxidase by methylmercaptoimidazole, thiouracil, and propylthiouracil in vitro and its relationship to in vivo findingsEndocrinology103(3),871-872(1978)
Cooper, D.S.Antithyroid drugsN. Engl. J. Med.352(9),905-917(2005)
Brock, R.E., and Head, W.F., Jr.Mechanisms of antithyroidal activity of methimazoleJ. Pharm. Sci.55(8),822-825(1966)
Allen, E.M., Rajatanavin, R., Nogimori, T., et al.The effect of methimazole on the development of spontaneous lymphocytic thyroiditis in the diabetes-prone BB/W ratAm. J. Med. Sci.292(5),267-271(1986)
Bortolotto, V.C., Pinheiro, F.C., Araujo, S.M., et al.Chrysin reverses the depressive-like behavior induced by hypothyroidism in female mice by regulating hippocampal serotonin and dopamineEur. J. Pharmacol.822,78-84(2018)
Bortolotto, V.C., Araujo, S.M., Pinheiro, F.C., et al.Modulation of glutamate levels and Na+,K+-ATPase activity contributes to the chrysin memory recovery in hypothyroidism micePhysiol. Behav.222,112892(2020)
