Trichlormethiazide
Cat. No.：YN481786
CAS No. ：133-67-5
规格
价格(RMB)
库存
| 产品名称: | Trichlormethiazide |
| CAS No.: | 133-67-5 |
| Chemical Name: | 6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide |
| Synonyms: | 三氯噻嗪 |
| 分子量: | 380.66 |
| 分子式: | C₈H₈Cl₃N₃O₄S₂ |
| SMILES: | O=S(C1=C(Cl)C=C(C2=C1)NC(C(Cl)Cl)NS2(=O)=O)(N)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trichlormethiazide 是一种具有口服生物活性的噻嗪类利尿剂，具有降压作用。Trichlormethiazide 可增加急性肾功能衰竭大鼠的 UV、Na 和 K 排泄，并有改善降低的肌酐清除率 (CCRE)。 |
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Shimizu, T., Yoshitomi, K., Nakamura, M., et al.Site and mechanism of action of trichlormethiazide in rabbit distal nephron segments perfused in vitroJ. Clin. Invest.82(2),721-730(1988)
Kähönen, M., Mäkynen, H., Arvola, P., et al.Arterial function after trichlormethiazide therapy in spontaneously hypertensive ratsJ. Pharmacol. Exp. Ther.272(3),1223-1230(1995)
Ueda, M., Matsuda, S., Tonda, K., et al.Antihypertensive effect of trichlormethiazide in spontaneously hypertensive ratsJpn. J. Pharmacol.28(4),617-626(1978)
