Acipimox
Cat. No.：YN481796
CAS No. ：51037-30-0
规格
价格(RMB)
库存
| 产品名称: | Acipimox |
| CAS No.: | 51037-30-0 |
| Chemical Name: | 5-methyl-2-pyrazinecarboxylic acid, 4-oxide |
| Synonyms: | 阿昔莫司; K-9321 |
| 分子量: | 154.12 |
| 分子式: | C₆H₆N₂O₃ |
| SMILES: | O=C(C1=C[N+]([O-])=C(C)C=N1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Acipimox (K-9321) 是一种烟酸类似物，具有抗脂抗脂肪分解的作用。Acipimox 可急性抑制脂解作用，抑制全身游离脂肪水平，改善胰岛素敏感性。 |
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Lovisolo, P.P., Briatico-Vangosa, G., Orsini, G., et al.Pharmacological profile of a new anti-lipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) (1) I - Mechanism of actionPharmacol. Res. Commun.13(2),151-161(1981)
Feipeng, J., Jiang, S., Yang, D., et al.Acipimox attenuates atherosclerosis and enhances plaque stability in ApoE-deficient mice fed a palmitate-rich dietBiochem. Bioph. Res. Commun.428(1),86-92(2012)
Kim, Y.W., Kim, J.Y., and Lee, S.K.Effects of phlorizin and acipimox on insulin resistance in STZ-diabetic ratsJ. Korean Med. Sci.10(1),24-30(1995)
