Penicillamine
Cat. No.:YN481797
产品名称: | Penicillamine |
CAS No.: | 52-67-5 |
Chemical Name: | 3-mercapto-D-valine |
Synonyms: | 青霉胺; D-(-) |
分子量: | 149.21 |
分子式: | C₅H₁₁NO₂S |
SMILES: | N[C@H](C(C)(S)C)C(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Penicillamine (D-(-)-Penicillamine) 是 penicillin 的代谢降解产物,可作为螯合剂,作用于威尔逊氏病。 |
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Delangle, P., and Mintz, E.Chelation therapy in Wilson's disease: From D-penicillamine to the design of selective bioinspired intracellular Cu(I) chelatorsDalton Trans.41(21),6359-6370(2012)
Abraham, E.P., Chain, E., Baker, W., et al.Penicillamine, a characteristic degradation product of penicillinNature151(3821),107(1943)
Domingo, J.L., Gómez, M., and Jones, M.M.Comparative efficacy of several potential treatments for copper mobilization in copper-overloaded ratsBiol. Trace Elem. Res.74(2),127-139(2000)
Klein, D., Lichtmannegger, J., Heinzmann, U., et al.Dissolution of copper-rich granules in hepatic lysosomes by D-penicillamine prevents the development of fulminant hepatitis in Long-Evans cinnamon ratsJ. Hepatol.32(2),193-201(2000)
Rahimi, N., Sadeghzadeh, M., Javad-Paydar, M., et al.Effects of D-penicillamine on pentylenetetrazole-induced seizures in mice: involvement of nitric oxide/NMDA pathwaysEpilepsy Behav.39,42-47(2014)