Tiopronin
Cat. No.：YN481806
CAS No. ：1953-02-2
规格
价格(RMB)
库存
| 产品名称: | Tiopronin |
| CAS No.: | 1953-02-2 |
| Chemical Name: | N-(2-mercapto-1-oxopropyl)-glycine |
| Synonyms: | 硫普罗宁 |
| 分子量: | 163.19 |
| 分子式: | C₅H₉NO₃S |
| SMILES: | O=C(O)CNC(C(S)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tiopronin 是一种可扩散的抗氧化剂，是重金属中毒的解毒剂和辐射防护剂。Tiopronin 可以控制胱氨酸沉淀和排泄的速度，有潜力用于胱氨酸尿症，类风湿性关节炎和肝病的研究。 |
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Rommain, M., Delecoeuillerie, G., Paul, J.L., et al.Inhibitory action of tiopronin on free radicalsRev. Rhum. Mal. Osteoartic.56(5 Pt 2),34-37(1989)
Yum, S., Park, H., Hong, S., et al.N-(2-mercaptopropionyl)-glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: Implication in amelioration of rat colitis by the antioxidantBiochem. Biophys. Res. Commun.443(3),1008-1013(2014)
Fujimoto, T., Fuyuta, M., Kiyofuji, E., et al.Prevention by tiopronin (2-mercaptopropionyl glycine) of methylmercuric chloride-induced teratogenic and fetotoxic effects in miceTeratology20(2),297-301(1979)
Date, M.O., Morita, T., Yamashita, N., et al.The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload modelJ. Am. Coll. Cardiol.39(5),907-912(2002)
Wang, J.Q., Zou, Y.H., Huang, C., et al.Protective effects of tiopronin against high fat diet-induced non-alcoholic steatohepatitis in ratsActa Pharmacol. Sin.33(6),791-797(2012)
