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Azacyclonol

Cat. No.:YN481827

  • CAS No. :115-46-8

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    • 产品名称: Azacyclonol
      CAS No.: 115-46-8
      Chemical Name: α,α-diphenyl-4-piperidinemethanol
      Synonyms:氮杂环醇; γ-pipradol
      分子量:267.37
      分子式:C₁₈H₂₁NO
      SMILES:OC(C1=CC=CC=C1)(C2CCNCC2)C3=CC=CC=C3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Azacyclonol即γ-pipradol,有消除精神病患者幻觉的活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Brown, D.A., and Quilliam, J.P.The effects of some centrally acting drugs on ganglionic transmission in the catBr. J. Pharmacol. Chemother.23(2),241-256(1964)

      Braun, D.L., Brown, B.B., and Feldman, R.G.The pharmacologic activity of α-(4-piperidyl)-benzhydrol hydrochloride (azacyclonol hydrochloride); an ataractive agent.J. Pharmacol. Exp. Ther.118(2),153-161(1956)

      Martens, J.Determination of the terfenadine metabolite azacyclonol in human serum using gas chromatography-mass spectrometryJ. Chromatogr. B Biomed. Appl.678(2),349-353(1996)

      Yun, C.H., Okerholm, R.A., and Guenggerich, F.P.Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylationDrug Metab. Dispos.21(3),403-409(1993)

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