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Dexrazoxane

Cat. No.:YN481835

  • CAS No. :24584-09-6

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    • 产品名称: Dexrazoxane
      CAS No.: 24584-09-6
      Chemical Name: 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-2,6-piperazinedione
      Synonyms:右雷佐生; ICRF-187; ADR-529; NSC-169780
      分子量:268.27
      分子式:C₁₁H₁₆N₄O₄
      SMILES:C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Dexrazoxane (ICRF-187) 是心脏保护剂。
      IC50和靶点:
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    • Yan, T., Deng, S., Metzger, A., et al.Topoisomerase IIα-dependent and -independent apoptotic effects of dexrazoxane and doxorubicinMol. Cancer Ther.8(5),1075-1085(2009)

      Kurz, T., Grant, D., Andersson, R.G.G., et al.Effects of MnDPDP and ICRF-187 on doxorubicin-induced cardiotoxicity and anticancer activityTransl. Oncol.5(4),252-259(2012)

      Junjing, Z., Yan, Z., and Baolu, Z.Scavenging effects of dexrazoxane on free radicalsJ. Clin. Biochem. Nutr.47(3),238-245(2010)

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