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Tocofersolan

Cat. No.:YN481852

  • CAS No. :9002-96-4

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    • 产品名称: Tocofersolan
      CAS No.: 9002-96-4
      Chemical Name: α-[4-[[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxy-poly(oxy-1,2-ethanediyl)
      Synonyms:TPGS; D-α-Tocopherol polyethylene glycol 1000 succinate; Vitamin E-TPGS
      分子量:1513.00
      分子式:暂无
      SMILES:CC1=C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)C2=C(C)C(C)=C1OC(CCC(OCCO)=O)=O.[n]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tocofersolan是一种合成的 α-生育酚的聚乙二醇衍生物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Sadoqi, M., Lau-Cam, C.A., and Wu, S.H.Investigation of the micellar properties of the tocopheryl polyethylene glycol succinate surfactants TPGS 400 and TPGS 1000 by steady state fluorometryJ. Colloid Interface Sci.333(2),585-589(2009)

      Collnot, E.-M., Baldes, C., Wempe, M.F., et al.Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: Influence on ATPase activity and membrane fluidityMol. Pharm.4(3),465-474(2007)

      Holloway, Z., Hawkey, A., Asrat, H., et al.The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[α]pyrene in early developmentNeurotoxicology86,78-84(2021)

      Liu, Y., Huang, L., and Liu, F.Paclitaxel nanocrystals for overcoming multidrug resistance in cancerMol. Pharm.7(3),863-869(2010)

      Yan, L., Su, Y., Hsia, I., et al.Delivery of anti-microRNA-21 by lung-targeted liposomes for pulmonary fibrosis treatmentMol. Ther. Nucleic Acids32,36-47(2023)

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