Fomepizole
Cat. No.：YN481889
CAS No. ：7554-65-6
规格
价格(RMB)
库存
| 产品名称: | Fomepizole |
| CAS No.: | 7554-65-6 |
| Chemical Name: | 4-methyl-1H-pyrazole |
| Synonyms: | 甲吡唑; 4-Methylpyrazole |
| 分子量: | 82.10 |
| 分子式: | C₄H₆N₂ |
| SMILES: | CC1=CNN=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fomepizole (4-Methylpyrazole) 是竞争性的乙醇脱氢酶 (alcohol dehydrogenase) 抑制剂。Fomepizole 可以阻止甲醇和乙二醇进一步转化为有毒代谢产物。Fomepizole 有潜力用于乙二醇或甲醇中毒的解毒剂。 |
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Blomstrand, R., Östling-Wintzell, H., Löf, A., et al.Pyrazoles as inhibitors of alcohol oxidation and as important tools in alcohol research: An approach to therapy against methanol poisoningProc. Natl. Acad. Sci. USA76(7),3499-3503(1979)
Brent, J., McMartin, K., Phillips, S., et al.Fomepizole for the treatment of methanol poisoningN. Engl. J. Med.344,424-429(2001)
