Acetohexamide
Cat. No.：YN481891
CAS No. ：968-81-0
规格
价格(RMB)
库存
| 产品名称: | Acetohexamide |
| CAS No.: | 968-81-0 |
| Chemical Name: | 4-acetyl-N-[(cyclohexylamino)carbonyl]-benzenesulfonamide |
| Synonyms: | 醋磺己脲 |
| 分子量: | 324.40 |
| 分子式: | C₁₅H₂₀N₂O₄S |
| SMILES: | O=S(C1=CC=C(C(C)=O)C=C1)(NC(NC2CCCCC2)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Acetohexamide是第一代磺脲类试剂，用于 2 型糖尿病的相关研究；刺激胰腺分泌胰岛素。 |
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Gopalakrishnan, M., Molinari, E.J., Char-Change, S., et al.Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K+ channel Kir6.2 combination expressed in HEK-293 cellsBr. J. Pharmacol.129(7),1323-1332(2000)
McMahon, R.E., Marshall, F.J., and Culp, H.W.The nature of the metabolites of acetohexamide in the rat and in the humanJ. Pharmacol. Exp. Ther.149(2),272-279(1965)
Imamura, Y., Sanai, K., Seri, K., et al.Hypoglycemic effect of S(-)-hydroxyhexamide, a major metabolite of acetohexamide, and its enantiomer R(+)-hydroxyhexamideLife Sci.69(16),1947-1955(2001)
