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Tolazamide

Cat. No.:YN481902

  • CAS No. :1156-19-0

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    • 产品名称: Tolazamide
      CAS No.: 1156-19-0
      Chemical Name: N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl-benzenesulfonamide
      Synonyms:甲磺氮草脲; U-17835
      分子量:311.40
      分子式:C₁₄H₂₁N₃O₃S
      SMILES:O=S(C1=CC=C(C)C=C1)(NC(NN2CCCCCC2)=O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tolazamide 是口服降血糖剂,用于研究 2 型糖尿病。
      IC50和靶点:
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    • Gopalakrishnan, M., Molinari, E.J., Char-Change, S., et al.Pharmacology of human sulphonylurea receptor SUR1 and inward rectifier K+ channel Kir6.2 combination expressed in HEK-293 cellsBr. J. Pharmacol.129(7),1323-1332(2000)

      Wang, P.H., Moeller, D., Flier, J.S., et al.Coordinate regulation of glucose transporter function, number, and gene expression by insulin and sulfonylureas in L6 rat skeletal muscle cellsJ. Clin. Invest.84(1),62-67(1989)

      Biederman, J.I., Vera, E., Rankhaniya, R., et al.Effects of sulfonylureas, α-endosulfine counterparts, on glomerulosclerosis in type 1 and type 2 models of diabetesKidney Int.67(2),554-565(2005)

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