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Hydrastine

Cat. No.:YN481907

  • CAS No. :118-08-1

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    • 产品名称: Hydrastine
      CAS No.: 118-08-1
      Chemical Name: (3S)-6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone
      Synonyms:北美黄连碱; (-)-β
      分子量:383.39
      分子式:C₂₁H₂₁NO₆
      SMILES:O=C1O[C@H]([C@@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=C1C(OC)=C(OC)C=C5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Hydrastine是存在于Hydrastis canadensis和Ranunculaceae家族其他植物的一种天然生物碱。
      IC50和靶点:
      In Vitro:
      In Vivo:
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      Solvent & Solubility:
    • Kim, S.H., Shin, J.S., Lee, J.J., et al.Effects of hydrastine derivatives on dopamine biosynthesis in PC12 cellsPlanta Med.67(7),609-613(2001)

      Yin, S.Y., Kim, Y.M., Lee, J.J., et al.Enantio-selective inhibition of (1R,9S)- and (1S,9R)-β-hydrastines on dopamine biosynthesis in PC12 cellsNeuropharmacology47(7),1045-1052(2004)

      Yin, S.Y., Kim, Y.M., Lee, J.J., et al.Effects of (1R,9S)-β-hydrastine on intracellular calcium concentration in PC12 cellsBiol. Pharm. Bull.30(8),1547-1550(2007)

      Yin, S.Y., Jin, C.M., Yang, Y.J., et al.Inhibitory effects of (1R,9S)-β-Hydrastine on calcium transport in PC12 cellsArch. Pharm. Res.30(1),109-113(2007)

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