Hydroquinidine
Cat. No.:YN481926
产品名称: | Hydroquinidine |
CAS No.: | 1435-55-8 |
Chemical Name: | 10,11-dihydro-6'-methoxy-cinchonan-9S-ol |
Synonyms: | 氢化奎宁定; Dihydroquinidine; (+) |
分子量: | 326.43 |
分子式: | C₂₀H₂₆N₂O₂ |
SMILES: | O[C@@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@]3([H])[N@](C[C@@H]4CC)CC[C@H]4C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Hydroquinidine (Dihydroquinidine) 是 Quinidine (一种抗心律不齐药) 的衍生物。Hydroquinidine 可延长 QT 间隔,具有抗心律不齐的功效。 |
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Chimienti, M., Regazzi, M.B., La Rovere, M.T., et al.Comparison of the effectiveness of dihydroquinidine and quinidine on ventricular ectopy after acute and chronic administrationCardiovasc. Drugs Ther.2(5),679-686(1988)
Chézalviel, F., Weissenburger, J., Ertzbischoff, O., et al.Comparison of the cardiac electrophysiological effects of flecainide and hydroquinidine in anesthetized dog: Concentration-response relationshipJ. Cardiovasc. Pharmacol.15(1),50-56(1990)
Zhou, Q., He, J., Tang, Y., et al.A novel hydroquinidine imprinted microsphere using a chirality-matching N-acryloyl-L-phenylalanine monomer for recognition of cinchona alkaloidsJ. Chromatogr. A.1238,60-67(2012)
Hermida, J.S., Denjoy, I., Clerc, J., et al.Hydroquinidine therapy in Brugada syndromeJ. Am. Coll. Cardiol.43(10),1853-1860(2004)