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Hydroquinidine

Cat. No.:YN481926

  • CAS No. :1435-55-8

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    • 产品名称: Hydroquinidine
      CAS No.: 1435-55-8
      Chemical Name: 10,11-dihydro-6'-methoxy-cinchonan-9S-ol
      Synonyms:氢化奎宁定; Dihydroquinidine; (+)
      分子量:326.43
      分子式:C₂₀H₂₆N₂O₂
      SMILES:O[C@@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@]3([H])[N@](C[C@@H]4CC)CC[C@H]4C3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Hydroquinidine (Dihydroquinidine) 是 Quinidine (一种抗心律不齐药) 的衍生物。Hydroquinidine 可延长 QT 间隔,具有抗心律不齐的功效。
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    • Chimienti, M., Regazzi, M.B., La Rovere, M.T., et al.Comparison of the effectiveness of dihydroquinidine and quinidine on ventricular ectopy after acute and chronic administrationCardiovasc. Drugs Ther.2(5),679-686(1988)

      Chézalviel, F., Weissenburger, J., Ertzbischoff, O., et al.Comparison of the cardiac electrophysiological effects of flecainide and hydroquinidine in anesthetized dog: Concentration-response relationshipJ. Cardiovasc. Pharmacol.15(1),50-56(1990)

      Zhou, Q., He, J., Tang, Y., et al.A novel hydroquinidine imprinted microsphere using a chirality-matching N-acryloyl-L-phenylalanine monomer for recognition of cinchona alkaloidsJ. Chromatogr. A.1238,60-67(2012)

      Hermida, J.S., Denjoy, I., Clerc, J., et al.Hydroquinidine therapy in Brugada syndromeJ. Am. Coll. Cardiol.43(10),1853-1860(2004)

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