6α-Methylprednisolone 21-hemisuccinate sodium salt
Cat. No.：YN481954
CAS No. ：2375-03-3
规格
价格(RMB)
库存
| 产品名称: | 6α-Methylprednisolone 21-hemisuccinate sodium salt |
| CAS No.: | 2375-03-3 |
| Chemical Name: | (6α,11β)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione, monosodium salt |
| Synonyms: | Methylprednisolone sodium succinate; 6-Methylprednisolone succinate sodium |
| 分子量: | 496.53 |
| 分子式: | C₂₆H₃₃NaO₈ |
| SMILES: | C[C@@]12[C@](C(COC(CCC(O[Na])=O)=O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 6α-Methylprednisolone 21-hemisuccinate钠盐是一种糖皮质激素, 半衰期较Prednisolone长，是一种有效的抗炎剂。 |
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Vree, T.B., Lagerwerf, A.J., Verwey-van Wissen, C.P., et al.High-performance liquid chromatography analysis, preliminary pharmacokinetics, metabolism and renal excretion of methylprednisolone with its C6 and C20 hydroxy metabolites in multiple sclerosis patients receiving high-dose pulse therapyJ. Chromatogr. B Biomed. Sci. Appl.732(2),337-348(1999)
Hori, T., Jin, L., Fujii, A., et al.Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 geneXenobiotica42(7),614-623(2012)
Avnir, Y., Ulmansky, R., Wasserman, V., et al.Amphipathic weak acid glucocorticoid prodrugs remote-loaded into sterically stabilized nanoliposomes evaluated in arthritic rats and in a Beagle dog: A novel approach to treating autoimmune arthritisArthritis Rheum.58(1),119-129(2008)
