Fenbufen
Cat. No.：YN481976
CAS No. ：36330-85-5
规格
价格(RMB)
库存
| 产品名称: | Fenbufen |
| CAS No.: | 36330-85-5 |
| Chemical Name: | γ-oxo-[1,1′-biphenyl]-4-butanoic acid |
| Synonyms: | 芬布芬; CL-82204 |
| 分子量: | 254.28 |
| 分子式: | C₁₆H₁₄O₃ |
| SMILES: | O=C(O)CCC(C1=CC=C(C2=CC=CC=C2)C=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fenbufen 是一种具有口服活性的非甾体抗炎化合物，具有镇痛、解热作用。Fenbufen 在各种动物模型中都有强大的活性，包括角叉菜素水肿、紫外线红斑、佐剂性关节炎等。 |
| IC50和靶点: | [{name:"COX-1:3.9 μM (IC50)"},{name: "COX-2:8.1 μM (IC50)"},{name: "Caspase-1:4.4 μM (IC50)"},{name: "Caspase-3:1.2 μM (IC50)"},{name: "Caspase-4:0.57 μM (IC50)"},{name: "Caspase-5:0.87 μM (IC50)"},{name: "Caspase-9:0.76 μM (IC50)"}] |
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| Solvent & Solubility: |
Kerwar, S.S.Pharmacologic properties of fenbufenAm. J. Med.75(4B),62-69(1983)
Brodgen, R.N., Heel, R.C., Speight, T.M., et al.Fenbufen: A review of its pharmacological properties and therapeutic use in rheumatic diseases and acute painDrugs21(1),1-22(1981)
