CP-24879 hydrochloride
Cat. No.:YN1710035
CAS No. :10141-51-2
产品名称: | CP-24879 hydrochloride |
CAS No.: | 10141-51-2 |
Chemical Name: | 4-(3-methylbutoxy)-benzenamine, monohydrochloride |
Synonyms: | |
分子量: | 215.8 |
分子式: | C11H17NO • HCl |
SMILES: | NC1=CC=C(C=C1)OCCC(C)C.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CP-24879 (hydrochloride) 是一种有效且选择性的delta5D/delta6D联合抑制剂。CP-24879 (hydrochloride) 能显著降低肝细胞内脂质积聚和炎症损伤。CP-24879 (hydrochloride) 在脂肪-1 和 ω-3 处理的肝细胞中表现出优越的抗脂肪变性和抗炎作用,可用于非酒精性脂肪性肝炎的研究。 |
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Obukowicz, M.G., Raz, A., Pyla, P.D., et al.Identification and characterization of a novel Δ6/Δ5 fatty acid desaturase inhibitor as a potential anti-inflammatory agentBiochem. Pharmacol.55,1045-1058(1998)
Levin, G., Duffin, K.L., Obukowicz, M.G., et al.Differential metabolism of dihomo-γ-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: Implications for cellular synthesis of prostaglandin E1 and prostaglandin E2Biochem. J.365(Pt 2),489-496(2002)