Lin28-let-7 antagonist 1
Cat. No.：YN1730127
CAS No. ：108825-65-6
| 产品名称: | Lin28-let-7 antagonist 1 |
| CAS No.: | 108825-65-6 |
| Chemical Name: | N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]-acetamide |
| Synonyms: | |
| 分子量: | 281.3 |
| 分子式: | C15H15N5O |
| SMILES: | CN(C(C)=O)C1=CC=CC(C(C=C2)=NN3C2=NN=C3C)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lin28-let-7 antagonist 1 (compound 1632) 是一种有效的Lin28/pre-let-7相互作用的拮抗剂。Lin28-let-7 antagonist 1 抑制 Lin28A 与 pre-let-7a-2 的结合，其IC50为 8 μM。Lin28-let-7 antagonist 1 抑制人类癌细胞的增殖。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Roos, M., Pradère, U., Ngondo, R.P., et al.A small-molecule inhibitor of Lin28ACS Chem Biol.11(10),2773-2781(2016)
