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Rivaroxaban-d4

Cat. No.:YN1570017

  • CAS No. :1132681-38-9

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    • 产品名称: Rivaroxaban-d4
      CAS No.: 1132681-38-9
      Chemical Name: 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-2,3,5,6-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
      Synonyms:BAY 59-7939-d
      分子量:439.9
      分子式:C19H14ClD4N3O5S
      SMILES:O=C1N(C2=C([2H])C([2H])=C(N3C[C@H](CNC(C4=CC=C(Cl)S4)=O)OC3=O)C([2H])=C2[2H])CCOC1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Rivaroxaban-d4是 Rivaroxaban 的氘代物。Rivaroxaban 是一种高效,选择性凝血因子 Xa (FXa) 抑制剂,IC50为 0.7 nM,Ki为 0.4 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Turpie, A.G.G.Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseasesArterioscler. Thromb. Vasc. Biol.27(6),1238-1247(2007)

      Babilonia, K., and Trujillo, T.The role of prothrombin complex concentrates in reversal of target specific anticoagulantsThromb. J.12:8,(2014)

      Turpie, A.G.G.Rivaroxaban as an oral anticoagulant for stroke prevention in atrial fibrillationTher. Clin. Risk Manag.10,197-205(2014)

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