Rivaroxaban-d4
Cat. No.:YN1570017
产品名称: | Rivaroxaban-d4 |
CAS No.: | 1132681-38-9 |
Chemical Name: | 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-2,3,5,6-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide |
Synonyms: | BAY 59-7939-d |
分子量: | 439.9 |
分子式: | C19H14ClD4N3O5S |
SMILES: | O=C1N(C2=C([2H])C([2H])=C(N3C[C@H](CNC(C4=CC=C(Cl)S4)=O)OC3=O)C([2H])=C2[2H])CCOC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Rivaroxaban-d4是 Rivaroxaban 的氘代物。Rivaroxaban 是一种高效,选择性凝血因子 Xa (FXa) 抑制剂,IC50为 0.7 nM,Ki为 0.4 nM。 |
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Turpie, A.G.G.Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseasesArterioscler. Thromb. Vasc. Biol.27(6),1238-1247(2007)
Babilonia, K., and Trujillo, T.The role of prothrombin complex concentrates in reversal of target specific anticoagulantsThromb. J.12:8,(2014)
Turpie, A.G.G.Rivaroxaban as an oral anticoagulant for stroke prevention in atrial fibrillationTher. Clin. Risk Manag.10,197-205(2014)