Pritelivir mesylate
Cat. No.：YN1590012
CAS No. ：1428333-96-3
| 产品名称: | Pritelivir mesylate |
| CAS No.: | 1428333-96-3 |
| Chemical Name: | N-[5-(Aminosulfonyl)-4-methyl-2-thiazolyl]-N-methyl-4-(2-pyridinyl)-benzeneacetamide Methanesulfonate Salt; N-[5-(Aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide Methanesulfonate Salt; Pritelivir Methanesulfonate; |
| Synonyms: | AIC316 mesylate; BAY 57-1293 mesylate |
| 分子量: | 498.587 |
| 分子式: | C19H22N4O6S3 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pritelivir mesylate (BAY 57-1293 mesylate) 是一种病毒解旋酶-引物酶复合物 (helicase-primase complex) 抑制剂，在体外和单纯疱疹病毒 (HSV) 感染的动物模型中均具有抗病毒活性。Pritelivir mesylate 对 1 型和 2 型单纯疱疹病毒 (HSV-1和HSV-2) 具有活性，对 HSV1-2 的 IC50为 0.02 μM。 |
| IC50和靶点: | [{name:"HSV-1:0.02 μM (IC50)"},{name: "HSV-2:0.02 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kleyman, G., et al.: Nat. Med., 8, 392 (2002)
Wozniak, M.A., et al.: Antiviral Res., 99, 401 (2013)
