PAPA NONOate
Cat. No.:YN1580005
产品名称: | PAPA NONOate |
CAS No.: | 146672-58-4 |
Chemical Name: | (Z)-1-[N-(3-aminopropyl)-N-(n-propyl)amino]diazen-1-ium-1,2-diolate |
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分子量: | 176.2 |
分子式: | C6H16N4O2 |
SMILES: | [NH3+]CCCN(N(N=O)[O-])CCC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PAPA NONOate 是NO 供体,一氧化氮释放半衰期为 77 分钟 (22-25°C)。PAPA NONOate 可能是一种潜在的研究糖尿病伤口愈合障碍的物质,通过增加伤口部位的胶原合成率。 |
IC50和靶点: | |
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Hrabie, J.A., Klose, J.R., Wink, D.A., et al.New nitric oxide-releasing zwitterions derived from polyaminesJ. Org. Chem.58,1472-1476(1993)
Keefer, L.K., Nims, R.W., Davies, K.M., et al."NONOates" (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage formsMethods Enzymol.268,281-293(1996)