(+)-(3R,8S)-Falcarindiol
Cat. No.：YN1710051
| 产品名称: | (+)-(3R,8S)-Falcarindiol |
| CAS No.: | 225110-25-8 |
| Chemical Name: | (3R,8S,9Z)-1,9-heptadecadiene-4,6-diyne-3,8-diol |
| Synonyms: | (3R,8S |
| 分子量: | 260.37126 |
| 分子式: | C17H24O2 |
| SMILES: | CCCCCCC/C=C\[C@H](O)C#CC#C[C@H](O)C=C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (+)-(3R,8S)-Falcarindiol 是从胡萝卜中得到的聚乙炔，具有抗分歧杆菌 (antimycobacterial) 作用，对Mycobacterium tuberculosisH37Ra 的最低抑制浓度 MIC 和 IC50值分别为 24 μM 和 6 μM。具有抗肿瘤和抗炎作用。 |
| IC50和靶点: | |
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O'Neill, T., Johnson, J.A., Webster, D., et al.The Canadian medicinal plant Heracleum maximum contains antimycobacterial diynes and furanocoumarinsJ. Ethnopharmacol.147(1),232-237(2013)
Zheng, X., Zheng, X., Zhang, C., et al.Cytotoxic polyacetylenes isolated from the roots and rhizomes of Notopterygium incisumChinese Chem. Lett.30(2),428-430(2019)
Tamura, S., Ohno, T., Hattori, Y., et al.Establishment of absolute stereostructure of falcarindiol, algicidal principle against Heterocapsa circularisquama from Notopterygii RhizomaTetrahedron Lett.51(11),1523-1525(2010)
