D-AP4
Cat. No.:YN1730156
产品名称: | D-AP4 |
CAS No.: | 78739-01-2 |
Chemical Name: | (2R)-2-Amino-4-phosphonobutanoic Acid; (R)-2-Amino-4-phosphonobutanoic Acid; D-(-)-2-Amino-4-phosphonobutanoic Acid; D-(-)-2-Amino-4-phosphonobutyric Acid; D-2-Amino-4-phosphonobutanoic Acid; D-2-Amino-4-phosphonobutyric Acid; |
Synonyms: | D-APB; D-2-Amino-4-phosphonobutyric acid |
分子量: | 183.1 |
分子式: | C4H10NO5P |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid) 是谷氨酸的磷酸类似物,是NMDA广谱兴奋性氨基酸受体拮抗剂。D-AP4 也是海马 CA1 锥体神经元中 quisqualate-sensitized AP6 部位的激动剂。D-AP4 抑制 AMPA 受体刺激培养的小脑颗粒细胞中的 57Co2+内流 (IC50≥ 100 μM)。 |
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