Nonapeptide-1
Cat. No.：YN1720125
| 产品名称: | Nonapeptide-1 |
| CAS No.: | 158563-45-2 |
| Chemical Name: | |
| Synonyms: | Melanostatine-5 |
| 分子量: | 1206.52 |
| 分子式: | C61H87N15O9S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nonapeptide-1 (Melanostatine-5)，一种多肽类激素，是MC1R选择性拮抗剂 (Ki: 40 nM)。 Nonapeptide-1 是一种竞争性的α-MSH拮抗剂，可有效抑制黑素细胞中 α-MSH 诱导的细胞内cAMP和黑素体扩散 (IC50分别为 2.5 nM 和 11 nM)。 Nonapeptide-1 抑制黑色素合成，可用于研究皮肤色素沉着和肾上腺类固醇生成的调节、皮肤癌。 |
| IC50和靶点: | [{name:"MC1R:40 nM (Ki)"},{name: "MC3R:0.47 μM (Ki)"},{name: "MC4R:1.34 μM (Ki)"},{name: "MC5R:2.4 μM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
