Aureusimine B
Cat. No.：YN1590031
| 产品名称: | Aureusimine B |
| CAS No.: | 170713-71-0 |
| Chemical Name: | 3-(1-methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone |
| Synonyms: | Phevalin |
| 分子量: | 228.3 |
| 分子式: | C14H16N2O |
| SMILES: | CC(C)C1=NC=C(NC1=O)CC2=CC=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aureusimine B (Phevalin) 是一种可由金黄色葡萄球菌生物膜产生的环状二肽。Aureusimine B 可用作慢性金黄色葡萄球菌生物膜感染的潜在生物标志物和/或治疗靶点。 |
| IC50和靶点: | |
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Alvarez, M.E., White, C.B., Gregory, J., et al.Phevalin, a new calpain inhibitor, from a Streptomyces spJ. Antibiot. (Tokyo)48(10),1165-1167(1995)
Zimmermann, M., and Fischbach, M.A.A family of pyrazinone natural products from a conserved nonribosomal peptide synthetase in Staphylococcus aureusChem. Biol.17(9),925-930(2010)
Secor, P.R., Jennings, L.K., James, G.A., et al.Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expressionPLoS One7(7),(2012)
Wyatt, M.A., Wang, W., Roux, C.M., et al.Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulenceScience329(5989),294-296(2010)
