Rucaparib Camsylate
Cat. No.:YN290048
CAS No. :1859053-21-6
产品名称: | Rucaparib Camsylate |
CAS No.: | 1859053-21-6 |
Chemical Name: | Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)-, compd. with 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one |
Synonyms: | 瑞卡帕布樟脑磺酸盐 |
分子量: | 555.66 |
分子式: | C₂₉H₃₄FN₃O₅S |
SMILES: | FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1.O=S(C[C@@]5(C6(C)C)C(C[C@@]6([H])CC5)=O)(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Rucaparib Camsylate 是PARP的抑制剂,对 PARP1 的Ki值为 1.4 nM。Rucaparib Camsylate 也可结合 PARP 其他八个结构域。 |
IC50和靶点: | [{name:"PARP-1:1.4 nM (Ki)'}, 'PARP-2', 'PARP-3'] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Gillmore, A.T.
et al.: Org. Process Res. Dev., 16, 1897 (2012)