Rucaparib
Cat. No.：YN290066
CAS No. ：283173-50-2
| 产品名称: | Rucaparib |
| CAS No.: | 283173-50-2 |
| Chemical Name: | 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one |
| Synonyms: | 瑞卡帕布; AG014699; PF-01367338 |
| 分子量: | 323.36 |
| 分子式: | C₁₉H₁₈FN₃O |
| SMILES: | FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rucaparib (AG014699) 是一种具有口服活性的、有效的PARP抑制剂，对 PARP1 的Ki值为 1.4 nM，对其他八种 PARP 结构域也有亲和性。 |
| IC50和靶点: | [{name:"PARP-1:1.4 nM (Ki)'}, 'PARP-2', 'PARP-3'] |
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| Solvent & Solubility: |
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