3-Aminobenzamide
Cat. No.：YN290167
| 产品名称: | 3-Aminobenzamide |
| CAS No.: | 3544-24-9 |
| Chemical Name: | 3-amino-benzamide |
| Synonyms: | PARP-IN-1 |
| 分子量: | 136.15 |
| 分子式: | C₇H₈N₂O |
| SMILES: | O=C(C1=CC=CC(N)=C1)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3-Aminobenzamide (PARP-IN-1) 是一种有效的PARP抑制剂，在 CHO 细胞中，对 PARP 的IC50值约为 50 nM。 |
| IC50和靶点: | [{name:"PARP:50 nM (IC50)"}] |
| In Vitro: | |
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| Solvent & Solubility: |
Rankin, P.W., Jacobson, E.L., Benjamin, R.C., et al.Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivoJ. Biol. Chem.264(8),4312-4317(1989)
Caldini, R., Fanti, E., Magnelli, L., et al.Low doses of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, stimulate angiogenesis by regulating expression of urokinase type plasminogen activator and matrix metalloprotease 2Vasc. Cell3(1),12(2011)
Beneke, S., Cohausz, O., Malanga, M., et al.Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1Nucleic Acids Res.36(19),6309-6317(2008)
