Nudifloramide
Cat. No.:YN310137
产品名称: | Nudifloramide |
CAS No.: | 701-44-0 |
Chemical Name: | 1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxamide |
Synonyms: | 2PY |
分子量: | 152.15 |
分子式: | C₇H₈N₂O₂ |
SMILES: | O=C(C(C=C1)=CN(C)C1=O)N |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Nudifloramide (2PY) 是烟酰胺-腺嘌呤二核苷酸 (NAD) 降解的最终产物之一。Nudifloramide 在体外可显著抑制PARP-1活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Giner, M.P., Christen, S., Bartova, S., et al.A method to monitor the NAD+ metabolome - from mechanistic to clinical applicationsInt. J. Mol. Sci.22(19),10598(2021)
Lenglet, A., Liabeuf, S., Bodeau, S., et al.N-methyl-2-pyridone-5-carboxamide (2PY)-Major metabolite of nicotinamide: An update on an old uremic toxinToxins (Basel)8(11),E339(2016)
Rutkowski, B., Rutkowski, P., Słomińska, E., et al.Distribution of purine nucleotides in uremic fluids and tissuesJ. Ren. Nutr.20(5 Suppl),S7-10(2010)