PARP14 inhibitor H10
Cat. No.:YN310146
产品名称: | PARP14 inhibitor H10 |
CAS No.: | 2084811-68-5 |
Chemical Name: | |
Synonyms: | H10 |
分子量: | 557.58 |
分子式: | C₂₄H₂₇N₇O₇S |
SMILES: | O=C(O)C1=CC=CC(S(=O)(NCCN2N=NC(CCNC(CCC(NC3=CC=CC(C(N)=O)=C3)=O)=O)=C2)=O)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PARP14 inhibitor H10 (化合物 H10) 是针对PARP14的选择性抑制剂 (IC50=490 nM),是其他 PARP 的抑制剂 (约为 PARP1 的 24 倍)。PARP14 抑制剂 H10 诱导 caspase-3/7 介导的细胞凋亡 (apoptosis)。 |
IC50和靶点: | [{name:"PARP14:490 nM (IC50)'}, 'PARP1'] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |