5,7-Dihydroxychromone
Cat. No.：YN310353
| 产品名称: | 5,7-Dihydroxychromone |
| CAS No.: | 31721-94-5 |
| Chemical Name: | 5,7-dihydroxy-4H-1-benzopyran-4-one |
| Synonyms: | 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮 |
| 分子量: | 178.14 |
| 分子式: | C₉H₆O₄ |
| SMILES: | O=C1C=COC2=CC(O)=CC(O)=C12 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 5,7-Dihydroxychromone 是一种Cudrania tricuspidata的提取物，可以激活Nrf2/ARE信号并对 6-OHDA 诱导的氧化应激和细胞凋亡发挥神经保护作用。5,7-Dihydroxychromone 抑制 6-OHDA 诱导的 SH-SY5Y 细胞中活化的caspase-3，caspase-9以及切割的PARP的表达。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Vaughn, S.F.Phytotoxic and antimicrobial activity of 5,7-dihydroxychromone from peanut shellsJ. Chem. Ecol.21(2),107-115(1995)
Kim, D.-W., Lee, K.-t., Kwon, J., et al.Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathwayLife Sci.130,25-30(2015)
