Paris saponin VII
Cat. No.:YN310360
产品名称: | Paris saponin VII |
CAS No.: | 68124-04-9 |
Chemical Name: | |
Synonyms: | Chonglou Saponin VII |
分子量: | 1031.18 |
分子式: | C₅₁H₈₂O₂₁ |
SMILES: | O[C@@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(C[C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O[C@@]7([H])[C@@H]([C@@H]([C@@H](O[C@@]8([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O8)O)O)[C@H](C)O7)O)O)[C@@H](CO)O6)O)O[C@@]9([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O9)O)O)CC5)=CC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Paris saponin VII (Chonglou Saponin VII) 是从延龄草 (Trillium tschonoskii Maxim) 的根和根茎中分离的甾体皂苷。Paris saponin VII 诱导的 K562/ADR 细胞凋亡与Akt/p38 MAPK和P-gp的抑制有关。Paris saponin VII 减弱线粒体膜电位,增加凋亡相关蛋白 (如 Bax 和细胞色素 c) 的表达,并降低Bcl-2,caspase-9,caspase-3,PARP-1 和 p-Akt的蛋白表达水平 |
IC50和靶点: | |
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Clinical Trial: | |
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