Vorolanib
Cat. No.：YN440116
CAS No. ：1013920-15-4
规格
价格(RMB)
库存
| 产品名称: | Vorolanib |
| CAS No.: | 1013920-15-4 |
| Chemical Name: | N-[(3S)-1-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide; X-82 (Vorolanib); |
| Synonyms: | CM082; X-82 |
| 分子量: | 439.48 |
| 分子式: | C₂₃H₂₆FN₅O₃ |
| SMILES: | O=C1/C(C2=CC(F)=CC=C2N1)=C/C(NC(C)=C3C(N[C@@H]4CN(C(N(C)C)=O)CC4)=O)=C3C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vorolanib (CM082) 是一种具有口服活性的，有效的VEGFR/PDGFR抑制剂。Vorolanib 是一种有效的 ATP 结合盒 (ABC) 转运蛋白抑制剂。Vorolanib 是一种血管生成抑制剂，与 ZD1839 (HY-50895) 联用具有抗肿瘤活性。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Pedersen, K. S., et al.: Invest. New Drugs, PagesAhead of Print (2021)
Dan, H., et al.: Microvasc. Res., 136, 104146 (2021)
